Traveling from the East on I-10 - Saguaro National Park - Eastern District
If you are driving on Interstate 10 and entering Tucson from the East to get to the Saguaro National Park - Eastern District. Take Houghton Road exit (275) north to Escalante Road ( about 8 miles ) take a right onto Escalante Road and go about 2 miles to dead end into Old Spanish Trail on the boundary with Saguaro National Park East. Take a left and go 400 yards or so and the park entrance is on the right. Look for signs to Saguaro National Park.