Going on US 16 is the best way to go. Starting from Buffalo, it's about 15 - 20 miles to Crazy Woman road. It's best to have a GPS, which will show when you are approacing Crazy Woman road. From US 16, Crazy Woman road is all down hill and to leave the canyon, just follow the road to Interstate 25.
I had to drop down to a lower elevation to find trees where the leaves hadn't fallen. I'll get there earlier next year.