The most direct route is to take Cove Creek Road (partially graveled). From interstate I-40, exit at North Carolina exit #20 and travel 0.2 miles on route 276. Turn right onto Cove Creek Road and follow the signs 11 miles into the Cataloochee Valley.
This is a divine auto tour, but make sure you get out and walk the trails too!
This is a shot of Palmer Chapel the only church in Cataloochee Valley with a beautiful morning fog rolling in.